Table 1.
Demographic, clinical, and behavioral characteristics of 7,944 CNICS patients six months after ART initiation, between 1 July 1998 and 30 June 2014, averaged over 100 imputations.
| Characteristic | Total n=7,944 |
<20 cpm n=4,545 |
20–999 cpm n=2,184 |
>999 cpm n=1,215 |
|---|---|---|---|---|
| No. (%) | No. (%) | No. (%) | No. (%) | |
| Age, years | 40 (32, 46) | 40 (32, 47) | 40 (33, 47) | 39 (32, 45) |
| Malea | 6,566 (82.7) | 3,790 (83.4) | 1,833 (83.9) | 943 (77.6) |
| Race/ethnicitya | ||||
| White, non-Hispanic | 3,581 (45.1) | 2,163 (47.6) | 971 (44.5) | 447 (36.8) |
| Black, non-Hispanic | 2,908 (36.6) | 1,482 (32.6) | 835 (38.2) | 591 (48.6) |
| Other, non-Hispanic | 401 (5.1) | 254 (5.6) | 101 (4.6) | 46 (3.8) |
| Hispanic | 1,054 (13.3) | 646 (14.2) | 277 (12.7) | 131 (10.8) |
| MSM, evera | 4,917 (61.9) | 2,946 (64.8) | 1,331 (60.9) | 640 (52.7) |
| IDU, evera | 979 (12.3) | 477 (10.5) | 277 (12.7) | 225 (18.5) |
| Smoking, ever | 2,605 (32.8) | 1,451 (31.9) | 708 (32.4) | 466 (36.7) |
| At-risk alcohol use, ever | 1,197 (15.1) | 654 (14.4) | 317 (14.5) | 226 (18.6) |
| Pre-ART viral load, cpmb | 74,827 (22,394; 237,780) | 56,048 (17,593; 170,000) | 111,880 (36,295; 372,848) | 93,928 (30,900; 294,966) |
| Year of ART initiationb | 2007 (2003, 2010) | 2008 (2004, 2010) | 2006 (2002, 2009) | 2004 (2001, 2008) |
| ART regimenb | ||||
| NNRTI-based | 3,747 (47.2) | 2,463 (54.2) | 852 (39.0) | 432 (35.6) |
| PI-based | 3,188 (40.1) | 1,519 (33.4) | 1,048 (48.0) | 621 (51.1) |
| INSTI-based | 431 (5.4) | 313 (6.9) | 87 (4.0) | 31 (2.6) |
| Other | 578 (7.3) | 229 (5.5) | 198 (9.1) | 131 (10.8) |
| CD4 count, cells/mm3 | 349 (193, 532) | 405 (245, 574) | 321 (184, 496) | 191 (71, 355) |
| Clinical AIDS diagnosis | 2,313 (29.1) | 1,101 (24.2) | 740 (33.9) | 472 (38.9) |
| Chronic hepatitis B | 209 (2.6) | 91 (2.0) | 66 (3.0) | 52 (4.3) |
| Chronic hepatitis C | 650 (8.2) | 327 (7.2) | 177 (8.1) | 146 (12.0) |
| Past cancer diagnosis | 429 (5.4) | 240 (5.3) | 121 (5.5) | 68 (5.6) |
| Statin use, ever | 250 (3.2) | 167 (3.7) | 59 (2.7) | 24 (2.0) |
Abbreviations: AIDS, acquired immunodeficiency syndrome; ART, antiretroviral therapy; cpm, copies per milliliter; INSTI, integrase strand transfer inhibitor; IQR, interquartile range; NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor
a
Assessed at entry into CNICS cohort.
b
Assessed at ART initiation.