Table 1.
Epidemiological Features and Clinical Histories of Study Patients With Advanced HIV Infection and Recent-Onset, Widespread Skin Lesions Suspicious for Systemic Mycoses
| Epidemiological or Clinical Characteristics | Systemic Mycoses (n = 25) |
Other Diagnoses (n = 8)a |
P Value |
|---|---|---|---|
| Age, median (IQR), y | 35 (31–42) | 36 (35–45) | .5 |
| Male | 20 (75) | 5 (63) | .4 |
| Occupational risk for exposure to disturbed soil | 8 (32) | 0 (0) | .2 |
| Appearance of skin lesions ≤4 weeks after ART initiation | 11 (44) | 0 (0) | .03 |
| Preexisting skin lesions that worsened after ART initiation | 5 (20) | 0 (0) | .3 |
| Duration of skin lesions, median (IQR), wk | 4 (3–10) | 8 (4–12) | .6 |
| Skin lesions pruritic | 7 (28) | 2/6 (33) | 1.0 |
| Skin lesions painful | 5 (20) | 1/6 () | 1.0 |
| Fever | 15/22 (68) | 4/7 (57) | .7 |
| Weight loss | 23 (92) | 4/5 (80) | .4 |
| Cough | 17 (68) | 3/6 (50) | .6 |
| Upper respiratory tract complaint | 16 (64) | 2 (25) | .2 |
Data are number/total number (%) unless otherwise specified.
Abbreviations: ART, antiretroviral therapy; IQR, interquartile range.
aOther diagnoses included tuberculosis (n = 1), syphilis (n = 2), papular pruritic eruption (n = 2), bacillary angiomatosis (n = 2), and lichen planus (n = 1).