Table 3.
Risk Factors for 28-Day In-Hospital Mortality
| Survivor | Nonsurvivor | P a | aOR | 95% CI | P b | |
|---|---|---|---|---|---|---|
| n | 311 | 55 | ||||
| Age, median (IQR) | 62 (49–74) | 63 (53–74) | .85 | |||
| Female | 161 (52) | 28 (51) | 1.0 | |||
| Race | .31 | |||||
| White | 173 (56) | 25 (45) | ||||
| Black | 114 (37) | 26 (47) | ||||
| Other | 24 (8) | 4 (7) | ||||
| Charlson comorbidity index ≥3 | 160 (51) | 31 (56) | .56 | |||
| Diabetes mellitus | 128 (41) | 24 (44) | .77 | |||
| Cardiac diseasec | 120 (39) | 24 (44) | .54 | |||
| Source | <.0001 | .001 | ||||
| Blood (ref.) | 66 (21) | 26 (47) | - | - | ||
| Urine | 105 (34) | 4 (7) | 0.16 | 0.05–0.51 | ||
| Respiratory | 66 (21) | 14 (25) | 0.27 | 0.12–0.65 | ||
| Other | 74 (24) | 11 (20) | 0.39 | 0.16–0.92 | ||
| Origin | .001 | |||||
| Home (ref.) | 122 (39) | 15 (27) | - | - | ||
| Skilled nursing facility | 125 (40) | 12 (22) | 0.63 | 0.26–1.48 | ||
| Hospital transfer | 49 (16) | 15 (27) | 1.93 | 0.81–4.66 | ||
| Long-term acute care hospital | 15 (5) | 13 (24) | 4.53 | 1.60–12.97 | ||
| Critical illnessd | 107 (34) | 40 (73) | <.0001 | 4.28 | 2.15–8.93 | <.0001 |
| RRT | 49 (16) | 22 (40) | <.001 | 2.27 | 1.09–4.68 | .03 |
All data expressed as n (% of survivors and nonsurvivors, respectively), unless otherwise indicated.
Abbbreviations: aOR, adjusted odds ratio; CI, confidence interval; IQR, interquartile range; RRT, renal replacement therapy.
a P value for univariable relationship with 28-day in-hospital mortality.
b P value for multivariable relationship with 28-day in-hospital mortality.
cCardiac disease defined as the presence of coronary artery disease and/or congestive heart failure.
dCritical illness defined as Pitt bacteremia score ≥4 at the time of index culture.