Table 3.

Example of Days of Therapy Calculation Per Patient

Drug	Dose/Frequency	Day 1	Day 2	Day 3	DOT
Piperacillin/tazobactum	4.5 mg every 6 h	4 doses	4 doses	2 doses	2.5
Vancomycin	1500 mg every 12 h	2 doses	2 doses	2 doses	3
Total DOT					5.5

Abbreviation: DOT, days of therapy.

Patient DOT was tallied for each cohort and divided by the total number of patients in each cohort (pre-PCT-A = 985, post-PCT-A = 1167). Antibiotic use and duration of therapy were tabulated to an increment of a quarter of a day.