Table 1.
Clinical Characteristics of Women With and Without Polycystic Ovarian Syndrome
| Characteristic | Nonobese |
Obese |
||
|---|---|---|---|---|
| PCOS Features | Non-PCOS | PCOS Features | Non-PCOS | |
| Subjects, n | 37 | 107 | 108 | 237 |
| Age, y | 40 (38, 41)a | 41 (39, 42) | 41 (39, 42)b | 42 (41, 43) |
| BMI, kg/m2 | 23.9 (23.0, 25.5) | 23.9 (22.8, 24.9) | 33.9 (32.5, 36.9)b | 32.1 (30.9, 33.3) |
| Waist girth, cm | 79 (77, 84) | 79 (75, 82) | 102 (98, 110)b | 99 (96, 100) |
| Hip girth, cm | 97 (94, 101) | 98 (97, 102) | 118 (114, 123)b | 115 (113, 117) |
| Waist/hip ratio | 0.82 (0.80, 0.86) | 0.81 (0.79, 0.83) | 0.87 (0.86, 0.88) | 0.85 (0.84, 0.87) |
| Total testosterone, nmol/L | 2.78 (2.08, 2.78)a | 1.74 (1.74, 2.08) | 2.78 (2.77, 3.12)b | 2.08 (2.08, 2.08) |
| Calculated free testosterone, pmol/L | 1.84 (1.51, 2.15)a | 1.41 (1.26, 1.52) | 2.19 (2.01, 2.37)b,d | 1.73 (1.61, 1.84) |
| SHBG, nmol/L | 149 (115, 188)a | 169 (157, 186) | 96 (91, 117)b | 123 (114, 139) |
| Free androgen index | 1.84 (1.08, 2.14)a | 1.15 (0.96, 1.28) | 2.83 (2.16, 3.12)b,d | 1.58 (1.43, 1.75) |
| Prevalence of clinical features, % | ||||
| Hirsutism | 81c | 25 | 88c | 25 |
| Oligomenorrhea | 73c | 8 | 87c | 8 |
| Polycystic ovaries | 78c | 21 | 85c | 17 |
| African-American | 57 | 39 | 47 | 50 |
| Premenopausal | 86 | 79 | 69 | 74 |
Data presented as median (95% confidence intervals).
a
Significantly different between nonobese (body fat <35%) PCOS and nonobese non-PCOS (P < 0.05).
b
Significantly different between obese (body fat ≥35%) PCOS and obese non-PCOS (P < 0.05).
c
Significantly different from non-PCOS within nonobese and obese subgroups (P < 0.05; χ2 test).
d
Significantly greater in obese PCOS than in all other subgroups (P = 0.04).