Table 4.
Metabolic Traits of Women With and Without Polycystic Ovarian Syndrome
| Variable | Nonobese |
Obese |
||
|---|---|---|---|---|
| PCOS Features | Non-PCOS | PCOS Features | Non-PCOS | |
| Glucose, mg/dL | 86 (80, 90) | 86 (82, 89) | 95 (91, 97) | 93 (91, 95) |
| Insulin, mU/mL | 8.3 (6.2, 10.2) | 7.8 (6.3, 8.9) | 17.3 (15.2, 19.4)a | 14.8 (13.4, 16.5) |
| HOMA-IR, % | 1.04 (0.78, 1.32) | 1.01 (0.84, 1.15) | 2.24 (1.94, 2.49)a | 1.91 (1.75, 2.15) |
| Triglycerides, mg/dL | 68 (51, 81) | 69 (59, 85) | 88 (81, 97) | 89 (83, 99) |
| Total cholesterol, mg/dL | 164 (150, 180) | 168 (163, 174) | 175 (162, 185) | 174 (166, 178) |
| VLDL cholesterol, mg/dL | 14 (10, 16) | 14 (12, 17) | 18 (16, 19) | 18 (17, 20) |
| LDL cholesterol, mg/dL | 91 (84, 98) | 95 (86, 101) | 102 (89, 112) | 103 (99, 107) |
| HDL cholesterol, mg/dL | 56 (49, 60) | 57 (52, 62) | 50 (47, 51) | 47 (46, 49) |
| CRP, mg/L | 1.1 (0.6, 2.0) | 1.2 (0.08, 1.9) | 5.3 (3.9, 6.9)a | 4.0 (3.0, 4.6) |
| Leptin, mg/L | 10.5 (8.3, 14.2) | 9.4 (7.9, 11.2) | 29.3 (26.4, 31.8) | 26.7 (24.9, 29.2) |
| Adiponectin, ng/mL | 9.0 (6.3, 10.6) | 9.7 (8.1, 10.6) | 5.9 (5.4, 6.8)a | 6.8 (6.1, 7.4) |
| Liver fat, % | 2.55 (1.49, 3.63) | 2.56 (2.08, 3.19) | 6.96 (5.37, 8.55)a | 4.44 (3.74, 4.94) |
| Prevalence of clinical features, % | ||||
| Hypertension | 27b | 12 | 33c | 24 |
| Type 2 diabetes mellitus | 0 | 5 | 13 | 11 |
| Metabolic syndrome | 19b | 13 | 46c | 39 |
| Current smoker | 54b | 28 | 17 | 20 |
Data presented as median (95% confidence intervals).
Abbreviations: LDL, low-density lipoprotein; VLDL, very-low-density lipoprotein.
a
Significantly different between obese PCOS and non-PCOS (P < 0.05).
b
Significantly different between nonobese PCOS and non-PCOS (P < 0.05; χ2 test).
c
Significantly different between obese PCOS and non-PCOS (P < 0.05; χ2 test).