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. Author manuscript; available in PMC: 2017 Nov 20.
Published in final edited form as: Bioorg Med Chem Lett. 2014 Oct 28;24(24):5801–5804. doi: 10.1016/j.bmcl.2014.10.026

Table 1.

Scheme 1 Analogues

Compound n Diamine
DZ 1 Homopiperazine
1 0 Homopiperazine
2 2 Homopiperazine
3 0 Piperazine
4 1 Piperazine
5 2 Piperazine
6 1 2,5-Dimethylpiperazine (±)
7 2 2,5-Dimethylpiperazine (±)
8 1 2,2-Dimethylpiperazine
9 2 2,2-Dimethylpiperazine
10 1 2,5-Diazabicyclo[2.2.2]octane (±)
11 2 2,5-Diazabicyclo[2.2.2]octane (±)