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. Author manuscript; available in PMC: 2017 Nov 20.
Published in final edited form as: Bioorg Med Chem Lett. 2014 Oct 28;24(24):5801–5804. doi: 10.1016/j.bmcl.2014.10.026

Table 3.

Scheme 3 Analogues

Compound n m Diamine X
27 1 2 Homopiperazine H
28 1 1 Piperazine H
29 0 2 Homopiperazine 4-OMe
30 1 2 Homopiperazine 4-OMe
31 1 1 Piperazine 4-OMe
32 0 1 Piperazine 4-OMe
33 0 2 Homopiperazine 3,5-(OMe)2
34 1 1 Piperazine 3,5-(OMe)2
35 1 1 Piperazine 3,5-(OMe)2
36 1 2 Homopiperazine 4-F
37 1 1 Piperazine 4-F