Table 5.
Age-Related Differences in the Relationship Between Gene Expression and Local Modularity
| Gene | All subjects | Younger subjects | Older subjects | Age effect |
|---|---|---|---|---|
| DISC1 | R = −0.25 | R = −0.02 | R = −0.26 | Driven by older subjects |
| p = 0.02 | p = 0.87 | p = 0.01a | ||
| DRD2 | R = −0.06 | R = 0.18 | R = −0.27 | Driven by older subjects |
| p = 0.57 | p = 0.10 | p = 0.009a | ||
| DTNBP1 | R = −0.23 | R = 0.02 | R = −0.31 | Driven by older subjects |
| p = 0.03 | p = 0.85 | p = 0.004a | ||
| GRM3 | R = 0.11 | R = 0.33 | R = −0.26 | Sign of relationship changes with age |
| p = 0.33 | p = 0.002a | p = 0.01a |
Gray highlight indicates age-related changes in the relationship between gene expression and local modularity.
Survived Bonferroni correction significance threshold of p = 0.016.