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. 2017 Nov 20;12(11):e0188375. doi: 10.1371/journal.pone.0188375

Table 1. Clinical characteristics of patients at the final visit for clinical study.

Tacrolimus group RASi group
Non-Tac Tac p-value Non-RASi RASi p-value
Number 19 18 19 18
Age (years) 41.0 ± 12.6 36.8 ± 11.3 0.258 37.0 ± 12.0 41.0 ± 12.0 0.284
Gender (male) 5 (26.3%) 6 (33.3%) 0.641 5 (26.3%) 6 (33.3%) 0.641
SBP (mmHg) 120 ± 11 123 ± 9 0.480 120 ± 11 123 ± 8 0.358
DBP (mmHg) 74 ± 8 74 ± 5 0.663 74.0 ± 8.0 74.0 ± 6.0 0.988
Hypertension 7 (36.8%) 9 (50.0%) 0.419 3 (15.8%) 13 (72.2%) 0.001
Diabetes mellitus 0 (0.0%) 1 (5.6%) 0.486 0 (0.0%) 1 (5.6%) 0.486
UPCR (g/g cr) 0.998 ± 0.479 0.649 ± 0.452 0.031 0.823 ± 0.453 0.824 ± 0.453 0.940
TA-proteinuria (g/g cr) 1.408 ± 0.441 0.611 ± 0.408 0.002 0.816 ± 0.477 0.856 ± 0.484 0.753
UACR (g/g cr) 0.711 ± 0.393 0.466 ± 0.406 0.036 0.594 ± 0.384 0.591 ± 0.453 0.799
Creatinine (mg/dL) 0.99 ± 0.27 1.10 ± 0.32 0.313 0.97 ± 0.24 1.12 ± 0.34 0.245
eGFR (mLmin/1.73 m2) 83.1 ± 24.1 77.4 ± 22.9 0.538 86.3 ± 23.9 74.1 ± 21.7 0.118
Albumin (g/dL) 4.2 ± 0.3 4.3 ± 0.3 0.425 4.1 ± 0.3 4.3 ± 0.3 0.061
Protein (g/dL) 7.1 ± 0.5 7.2 ± 0.5 0.988 7.1 ± 0.5 7.2 ± 0.5 0.343
CRP (mg/dL) 0.27 ± 0.69 0.13 ± 0.26 0.098 0.09 ± 0.11 0.32 ± 0.74 0.558
Hemoglobin (g/dL) 13.3 ± 1.3 12.9 ± 1.7 0.425 12.9 ± 1.6 13.2 ± 1.4 0.425
Hematuria 17 (89.5%) 15 (83.3%) 0.660 18 (94.7%) 14 (77.8%) 0.180
RASi 8 (42.1%) 10 (55.6%) 0.413 (-) (-) (-)
Tacrolimus (-) (-) (-) 8 (42.1%) 10 (55.6%) 0.413

Values expressed as either mean ± standard deviation, or number (percentage).