Table 1. Clinical characteristics of patients at the final visit for clinical study.
Tacrolimus group | RASi group | |||||
---|---|---|---|---|---|---|
Non-Tac | Tac | p-value | Non-RASi | RASi | p-value | |
Number | 19 | 18 | 19 | 18 | ||
Age (years) | 41.0 ± 12.6 | 36.8 ± 11.3 | 0.258 | 37.0 ± 12.0 | 41.0 ± 12.0 | 0.284 |
Gender (male) | 5 (26.3%) | 6 (33.3%) | 0.641 | 5 (26.3%) | 6 (33.3%) | 0.641 |
SBP (mmHg) | 120 ± 11 | 123 ± 9 | 0.480 | 120 ± 11 | 123 ± 8 | 0.358 |
DBP (mmHg) | 74 ± 8 | 74 ± 5 | 0.663 | 74.0 ± 8.0 | 74.0 ± 6.0 | 0.988 |
Hypertension | 7 (36.8%) | 9 (50.0%) | 0.419 | 3 (15.8%) | 13 (72.2%) | 0.001 |
Diabetes mellitus | 0 (0.0%) | 1 (5.6%) | 0.486 | 0 (0.0%) | 1 (5.6%) | 0.486 |
UPCR (g/g cr) | 0.998 ± 0.479 | 0.649 ± 0.452 | 0.031 | 0.823 ± 0.453 | 0.824 ± 0.453 | 0.940 |
TA-proteinuria (g/g cr) | 1.408 ± 0.441 | 0.611 ± 0.408 | 0.002 | 0.816 ± 0.477 | 0.856 ± 0.484 | 0.753 |
UACR (g/g cr) | 0.711 ± 0.393 | 0.466 ± 0.406 | 0.036 | 0.594 ± 0.384 | 0.591 ± 0.453 | 0.799 |
Creatinine (mg/dL) | 0.99 ± 0.27 | 1.10 ± 0.32 | 0.313 | 0.97 ± 0.24 | 1.12 ± 0.34 | 0.245 |
eGFR (mLmin/1.73 m2) | 83.1 ± 24.1 | 77.4 ± 22.9 | 0.538 | 86.3 ± 23.9 | 74.1 ± 21.7 | 0.118 |
Albumin (g/dL) | 4.2 ± 0.3 | 4.3 ± 0.3 | 0.425 | 4.1 ± 0.3 | 4.3 ± 0.3 | 0.061 |
Protein (g/dL) | 7.1 ± 0.5 | 7.2 ± 0.5 | 0.988 | 7.1 ± 0.5 | 7.2 ± 0.5 | 0.343 |
CRP (mg/dL) | 0.27 ± 0.69 | 0.13 ± 0.26 | 0.098 | 0.09 ± 0.11 | 0.32 ± 0.74 | 0.558 |
Hemoglobin (g/dL) | 13.3 ± 1.3 | 12.9 ± 1.7 | 0.425 | 12.9 ± 1.6 | 13.2 ± 1.4 | 0.425 |
Hematuria | 17 (89.5%) | 15 (83.3%) | 0.660 | 18 (94.7%) | 14 (77.8%) | 0.180 |
RASi | 8 (42.1%) | 10 (55.6%) | 0.413 | (-) | (-) | (-) |
Tacrolimus | (-) | (-) | (-) | 8 (42.1%) | 10 (55.6%) | 0.413 |
Values expressed as either mean ± standard deviation, or number (percentage).