Table 2. Renal histological damages induced by bilateral renal I/R, and effect of malva silvestris extract administration on them.
| Histopathology | Experimental Groups | ||||
|---|---|---|---|---|---|
| Sham | I/R | I/R+M200 | I/R+M400 | I/R+M600 | |
| Bowman's space enlargement | 0 | V | II | II | III |
| Intracellular vacuolization | 0 | III | I | II | II |
| Tubular cell necrosis | 0 | IV | I | I | II |
| Vascular congestion | I | IV | II | II | II |
| Intra-tubular proteinaceous casts | 0 | V | I | II | III |
| Total histopathologic score | 1 | 21** | 7‡ | 9*‡ | 12*‡ |
Histopathological scores in rats subjected to sham operation and received normal saline (Sham group), ischemia/reperfusion that received normal saline (I/R group), or different doses of malva silvestris (I/R+M groups).
* P<0.05,
**P<0.01, in comparison with sham group.
‡P<0.05, in comparison with I/R group.