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. 2017 Nov 20;12(11):e0188400. doi: 10.1371/journal.pone.0188400

Table 1. Top admixture association results in significant association regions.

The lead LAI provides the coordinates of the most significant local ancestry interval in the region. Ancestry freq provides the proportion of intervals inferred as inherited from the tested ancestry across the 12,116 individuals (24,232 chromosome). Effect size, SE and p-values were estimated based on the linear model for the effect of the local ancestry count on the trait.

Region Trait Tested ancestry Chr lead LAI Ancestry freq Effect size SE p-value
6p21.31 SBP Amerindian 6 (33971226, 34143292) 0.26 −1.31 0.29 6.57E-06
6p21.31 MAP Amerindian 6 (35923246, 36230135) 0.27 −0.92 0.21 8.14E-06
6p12.3 MAP African 6 (45501552, 45527132) 0.15 −1.06 0.26 5.52E-05
6p12.3 DBP African 6 (45501552, 45527132) 0.15 −0.96 0.23 3.19E-05
11q13.4 MAP Amerindian 11 (71243244, 71294802) 0.32 −0.85 0.21 4.67E-05
17q25.3 PP Amerindian 17 (78252770, 78392234) 0.30 0.79 0.19 2.29E-05