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. 2017 Sep 14;158(11):3738–3753. doi: 10.1210/en.2017-00098

Figure 3.

Figure 3.

YAP and TAZ are required for the maintenance of the adrenal cortex. (A−E) Photomicrographs comparing the adrenal glands of 20-week-old male (A) Yapflox/flox;Tazflox/flox, (B) Yapflox/+;Tazflox/+;Nr5a1cre/+, (C) Yapflox/+;Tazflox/flox;Nr5a1cre/+, (D) Yapflox/flox;Tazflox/+;Nr5a1cre/+, and (E) Yapflox/flox;Tazflox/flox;Nr5a1cre/+ mice. (F) Higher magnification of the boxed area in photomicrograph (E). (G, H) Photomicrographs comparing the adrenal glands of 20-week-old male (G) Yapflox/flox and (H) Yapflox/flox;Nr5a1cre/+ mice (arrows indicate multinuclear lipoid structures). Hematoxylin, phloxine, and saffron stain.