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. 2017 Sep 14;158(11):3738–3753. doi: 10.1210/en.2017-00098

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Figure 7. — Circulating hormone levels in male Yap^flox/flox;Taz^flox/flox;Nr5a1^cre/+ mice. (A) Serum corticosterone levels from untreated and ACTH-treated 10-week-old male Yap^flox/flox;Taz^flox/flox and Yap^flox/flox;Taz^flox/flox;Nr5a1^cre/+ mice. (B) Serum aldosterone levels from 20-week-old male Yap^flox/flox;Taz^flox/flox and Yap^flox/flox;Taz^flox/flox;Nr5a1^cre/+ mice. (C) Plasma ACTH levels in 10-week-old male Yap^flox/flox;Taz^flox/flox and Yap^flox/flox;Taz^flox/flox;Nr5a1^cre/+ mice. Sample numbers analyzed varied by hormonal test and genotype. Values for Yap^flox/flox;Taz^flox/flox mice were basal corticosterone: n = 17; ACTH-induced corticosterone: n = 6; aldosterone: n = 12; and ACTH: n = 7. Values for Yap^flox/flox;Taz^flox/flox;Nr5a1^cre/+ mice were basal corticosterone: n = 12; ACTH-induced corticosterone: n = 7; aldosterone: n = 9; and ACTH: n = 7. Data are expressed as mean (columns) ± standard error of the mean (error bars). Asterisks indicate significantly different from control (*P < 0.05).