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Bone strength, bone volume, and BMD in the femoral head, distal femur, and vertebrae after 14, 28, and 42 days of prednisolone administration. (A) Femoral head strength, modulus, and cancellous volume. (B) Midshaft femoral strength, femoral BMD, and distal femoral cancellous volume. (C) Vertebral strength, modulus, and BMD. Glucocorticoids decrease femoral head strength before decreasing femoral head cancellous bone volume. *P < 0.05; **P < 0.01; ***P < 0.001 (n = 3 to 8).
