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Femoral head cortical histomorphometry after 14, 28, and 42 days of prednisolone administration. (A) Endocortical bone formation rate and numbers of osteoblasts and osteoclasts. (B) Cortical area and width. Glucocorticoids rapidly decrease the number of osteoblasts and rate of bone formation while increasing the number of osteoclasts at endocortical margins. *P < 0.05; **P < 0.01; †P < 0.05 by Kruskal-Wallis test (n = 3 to 7).
