Figure 1.

Characterization of PNA animals. (A) Age and (B) body mass at vaginal opening in control (open symbols) and PNA (filled symbols) females. (C) Age and (D) body mass at preputial separation in control and PNA males. (E) Anogenital distance in adult female littermates of mice that were used for recording before puberty. (F) Representative estrous cycles in adult female littermates: *P < 0.05 control vs PNA, unpaired Student t test in all but (A) in which a Mann-Whitney U test was used. D, diestrus; E, estrus; P, proestrus.