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Spike timing in GnRH neurons changes with age in females and differs with PNA treatment in adults. (A) Log10 ISI distributions of GnRH recordings for each group of female mice. (B) Log10 ISI distribution for each group of male mice. Arrow indicates longer interval shoulder (see text). (C) Log10 ISI distributions comparing male control and female PNA mice, *P < 0.05, KS. Note change in color in panel (C) vs (A) and (B) for adult animals. CON, control.
