Table 3.
Genotypes associated with case/control (matched-pair) status.
| Discord. pairs* | Discord. pairs | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbSNP | allele | Maj Dom | Alter | p value | allele | Min Dom | alter | p value | total pairs |
| rs2305480, 17q21 | G | 15 | 28 | 0.066 | A | 39 | 55 | 0.121 | 205 |
| rs7216389, 17q21 | T | 20 | 34 | 0.076 | C | 39 | 55 | 0.121 | 209 |
| rs8076131, 17q21 | A | 15 | 28 | 0.066 | G | 41 | 53 | 0.256 | 207 |
| rs4795405, 17q21 | C | 18 | 30 | 0.111 | T | 37 | 53 | 0.113 | 206 |
| rs9303277, 17q21 | C | 17 | 33 | 0.033 | T | 37 | 47 | 0.326 | 194 |
| rs1558641, 2q11.2 | G | 0 | 2 | NA | A | 14 | 15 | 1.000 | 205 |
| rs10056340, 5q22.1 | G | 18 | 2 | 0.0008 | T | 67 | 30 | 0.0003 | 208 |
| rs6871536, 5q31 | T | 6 | 3 | 0.508 | C | 43 | 40 | 0.826 | 203 |
| rs928413, 9q21 | A | 2 | 2 | 1.000 | G | 29 | 26 | 0.788 | 203 |
| rs2155219, 11q13.4 | G | 47 | 31 | 0.089 | T | 46 | 37 | 0.380 | 206 |
“Discord. pairs” indicates the number of case/control pairs that are discordant for a particular genotype “Maj Dom”: where the major allele is dominant for the case. “Alter” indicates the alternate situation where the control genotype is dominant for the major allele. Similarly “Min Dom” indicates discordant pairs where the case genotype is dominant for the minor allele. “Total pairs” shows the total number of matched pairs, including both concordant and discordant pairs. “NA” refers to “not applicable”, eg less than 2 groups of discordant pairs.