Fig. 4.

The aggregated cone reflectance response. The figure shows the cone intrinsic reflectance response measured from the stimulated and control trials using all data from the condition illustrated by Fig. 3. (A) Repeat control and stimulated trials show a clear, measureable and reliable intrinsic reflectance response. The baseline is centered at 1 because Eq. (2) standardizes the response to the mean and standard deviation of the stimulus behavior. The warmer colors correspond to stimulated trials and the cooler colors correspond to control trials. (B) All trials for a given condition were then combined using pooled standard deviation, and the stimulus-evoked intrinsic reflectance response was taken as the difference between the stimulated and control pooled standard deviations. Signal gaps correspond to frames within each image sequence where the cone reflectance could not be measured due to failed registration (e.g. resulting from blinks or excessive eye motion). Stimulus duration indicated by the black bar. Data shown are from subject 11015 using a 550 nm, 337 nW/deg² stimuli.