Table 3.
Prevalence and adjusted odds ratios for individual physical conditions (standardized by age, sex, and deprivation score). Conditions are ordered by size of odds ratio (largest to smallest).
| Condition | Migraine n (%) |
No migraine n (%) |
Adjusted odds ratio (95% CI) |
|---|---|---|---|
| Total number of individuals | 9,370 (0.6) | 1,459,034 (99.4) | |
| Painful condition | 3,005 (32.1) | 123,229 (8.5) | 4.33 (4.12–4.55) |
| Constipation | 587 (6.3) | 35,913 (2.5) | 2.98 (2.72–3.26) |
| Dyspepsia | 1,300 (13.9) | 77,993 (5.4) | 2.42 (2.27–2.57) |
| Prostate disease | 58 (0.6) | 15,176 (1.0) | 2.24 (1.72–2.91) |
| Irritable bowel syndrome | 1,047 (11.2) | 51,286 (3.5) | 2.22 (2.08–2.37) |
| Epilepsy | 186 (2.0) | 12,379 (0.9) | 2.19 (1.89–2.54) |
| Chronic sinusitis | 167 (1.8) | 9,027 (0.6) | 2.11 (1.81–2.47) |
| Active asthma | 1,163 (12.4) | 86,587 (5.9) | 1.95 (1.84–2.08) |
| Multiple sclerosis | 81 (0.9) | 3,768 (0.3) | 1.94 (1.55–2.42) |
| Stroke or transient ischaemic attack | 281 (3.0) | 36,279 (2.5) | 1.66 (1.47–1.88) |
| Psoriasis or eczema | 103 (1.1) | 10,451 (0.7) | 1.57 (1.29–1.91) |
| Bronchiectasis | 31 (0.3) | 2,793 (0.2) | 1.53 (1.07–21.9); p=0.01 |
| Inflammatory arthritis and related conditions, including gout | 581 (6.2) | 57,600 (4.0) | 1.52 (1.39–1.65) |
| Inflammatory bowel disease | 111 (1.2) | 9,686 (0.7) | 1.52 (1.25–1.83) |
| Thyrotoxicosis/thyroid disorders, including hypothyroidism | 1,006 (10.7) | 71,077 (4.9) | 1.44 (1.35–1.54) |
| Diverticular disease | 286 (3.1) | 33,530 (2.3) | 1.43 (1.26–1.61) |
| Any new cancer in the last 5 years | 404 (4.3) | 43,422 (3.0) | 1.36 (1.23–1.50) |
| Hearing loss | 398 (4.3) | 55,333 (3.7) | 1.34 (1.21–1.49) |
| Peripheral vascular disease | 170 (1.8) | 23,122 (1.6) | 1.29 (1.10–1.50) |
| Diabetes | 569 (6.1) | 74,524 (5.1) | 1.23 (1.13–1.35) |
| Viral hepatitis | 8 (0.1) | 1,167 (0.1) | 1.23 (0.61–2.48); p=0.55 |
| Chronic kidney disease | 205 (2.2) | 33,362 (2.3) | 1.23 (1.07–1.43) |
| Visual impairment | 50 (2.9) | 8,485 (0.6) | 1.22 (0.92–1.62) |
| Coronary heart disease | 64 (0.7) | 81,019 (5.6) | 1.21 (1.10–1.34) |
| Hypertension | 1,798 (19.2) | 232,538 (15.9) | 1.18 (1.11–1.25) |
| Atrial fibrillation | 91 (1.0) | 23,887 (1.6) | 1.02 (0.82–1.26); p=0.83 |
| Glaucoma | 84 (0.9) | 15,844 (1.1) | 1.01 (0.81–1.26); p=0.88 |
| Parkinson’s disease | 10 (0.1) | 2,732 (0.2) | 1.00 (0.53–1.87); p=0.99 |
| Heart failure | 178 (6.7) | 18,840 (1.3) | 0.80 (0.62–1.02); p=0.08 |
| Cirrhosis/chronic liver disease/alcoholic liver disease | 11 (0.1) | 2,603 (0.2) | 0.64 (0.35–1.45); p=0.14 |
All differences significant at p<0.001, except where stated.