. Author manuscript; available in PMC: 2018 Sep 1.

Published in final edited form as: Lancet Psychiatry. 2017 Jul 24;4(9):706–714. doi: 10.1016/S2215-0366(17)30280-8

Table 4.

Adjusted odds ratios and 95% C.I. reflecting within-pair associations between cannabis use and suicidal thoughts and behaviours in MZ pairs. Only associations of discordant MZ pairs (Table 3) with significant unadjusted OR were reanalyzed with covariates^*.

	Discordant for Frequent (≥ 100 times; co – twin never user or lighter user)
Dependent Variable	OR	95% CI	χ²	p	N pairs
Major Depressive Disorder	1·681	(1·01, 2·80)	4·00	0·0455	198
Suicidal ideation	2·354	(1·24, 4·48)	6·82	0·0090	190
Suicidal ideation lasting >1 day	2·238	(0·89, 5·66)	2·89	0·0889	190
	Discordant for Frequent (≥ 100 times; co – twin is lighter user)
Dependent Variable	OR	95% CI	χ²	p	N pairs
Major Depressive Disorder	1·976	(1·11, 3·53)	5·30	0·0213	156
Suicidal ideation	2·466	(1·19, 5·10)	5·94	0·0148	147
Suicidal ideation lasting >1 day	2·719	(0·94, 7·85)	3·42	0·0643	147

Adjusted for conduct disorder (Table S4). Bootstrapped CI in Table S5.