Table 5.
Prevalence (95% CI) of major depressive disorder (MDD) and suicidal ideation (SI) in monozygotic twins from pairs concordant for frequent cannabis use and less frequent/never use, as well as in the frequent user and never/less frequent using member of discordant pairs.
| Twins from all MZ pairs | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Concordant | Discordant | Concordant | |||||||||
| Frequent | Frequent | Less Frequent/Never | N pairs | Less Frequent/Never | |||||||
| % | 95% CI | N pairs | % | 95% CI | % | 95% CI | % | 95% CI | N pairs | ||
| Major Depressive Disorder | 32·042 | (26·6, 37·5) | 142 | 32·663 | (26·1, 39·2) | 23·618 | (17·7, 29·5)a | 199 | 19·682 | (18·5, 20·9)a | 2200 |
| Suicidal ideation | 40·000 | (34·0, 46·0) | 130 | 32·105 | (25·5, 38·7) | 19·474 | (13·8, 25·1) | 190 | 17·182 | (16·0, 18·3) | 2101 |
| Twins from MZ pairs reporting lifetime cannabis use | |||||||||||
| Concordant | Discordant | Concordant | |||||||||
| Frequent | Frequent | Less Frequent | N pairs | Less Frequent | |||||||
| % | 95% CI | N pairs | % | 95% CI | % | 95% CI | % | 95% CI | N pairs | ||
| Major Depressive Disorder | 32·042 | (26·6, 37·5) | 142 | 33·333 | (25·9, 40·7) | 21·795 | (15·3, 28·3)a | 156 | 18·037 | (15·9, 20·2)a | 596 |
| Suicidal ideation | 40·000 | (34·0, 46·0) | 130 | 32·653 | (25·1, 40·2) | 18·367 | (12·1, 24·6) | 147 | 16·730 | (14·5, 19·0) | 523 |
a
The estimate for less frequent/never users from discordant pairs falls outside the 95% CI for the estimate from concordant pairs.