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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Hepatology. 2017 Oct 30;66(6):1952–1967. doi: 10.1002/hep.29374

Fig. 7.

Fig. 7

miR-206 displayed the strong therapeutic effect on HCC in cMyc mice. (A) Macroscopic (upper panel) and microscopic (lower panel) appearance of livers from cMyc mice treated with MC-TTR-miR-206 (n=6) or MC-TTR-miR-206-MM (control, n=6) stained with H&E (100×). (B) (B–C) Number of tumors and levels of miR-206, Ccnd1, Cdk6 and cMet in livers of mice treated with MC-TTR-miR-206 or MC-TTR-miR-206-MM. (D) Macroscopic (upper panel) and microscopic (lower panel) appearance of livers from cMyc mice treated with miR-206 mimic (n=6) or scramble (control, n=6) stained with H&E (100×). (E–F) Number of tumors and mRNA levels of Ccnd1, Cdk6 and cMet in livers of cMyc mice treated with miR-206 mimic or scramble. Data represent mean ± SEM. **p < 0.01.