Table 2.

Multivariable Cox Proportional Hazards Models for Likelihood of Undergoing Repeat Pulmonary Metastasectomy (PM)

Variable	Hazard Ratio (95% CI)	P
Age at diagnosis of primary tumor	0.98 (0.97 to 1.00)	0.033
Perioperative treatment at initial PM	0.67 (0.41 to 1.09)	0.10
Minimally invasive surgery at initial PM	1.58 (1.02 to 2.45)	0.041
Disease-free intervala	1.02 (1.00 to 1.04)	0.009
No. of pulmonary nodules at recurrence	0.73 (0.63 to 0.83)	<0.001
Synchronous extrapulmonary disease at recurrence	0.13 (0.08 to 0.23)	<0.001
KPS scale at recurrence (%)	1.01 (0.99 to 1.06)	0.14

KPS, Karnofsky Performance Status.

^aFrom first pulmonary metastasectomy to recurrence at any site per month.