Table 3.

Multivariable Cox Proportional Hazards Models for the Hazard of Death After Repeat Pulmonary Metastasectomy

Variable	Cox Hazard Ratio (95% CI)	P
Histologic subtype of primary tumor
PS/MFHa	1.00	—
Synovial	0.65 (0.33 to 1.28)	0.2
Leiomyosarcoma	0.48 (0.25 to 0.92)	0.026
Liposarcoma	0.42 (0.14 to 1.28)	0.13
Fibrosarcoma	0.44 (0.17 to 1.10)	0.077
MPNST	0.70 (0.16 to 3.13)	0.6
Other	1.04 (0.43 to 2.55)	0.9
High-grade primary tumor	1.89 (0.81 to 4.38)	0.14
Disease-free intervalb	0.98 (0.96 to 1.00)	0.11
Preoperative chemotherapy	1.94 (1.19 to 3.18)	0.008
No. of pulmonary nodules	1.13 (0.99 to 1.28)	0.073
Incomplete (R1/R2) resection	4.15 (2.26 to 7.62)	<0.001

PS/MFH, pleomorphic sarcoma/malignant fibrous histiocytoma; MPNST, malignant peripheral nerve sheath tumor.

^aReference group.

^bFrom first pulmonary metastasectomy to recurrence at any site per month.