. Author manuscript; available in PMC: 2018 Dec 1.

Published in final edited form as: Genet Epidemiol. 2017 Oct 29;41(8):824–833. doi: 10.1002/gepi.22084

Table 2. Simulations results for Empirical Type I Error and Power when the outcome is binary.

Simulation results for cohort study with N=5000, with disease prevalence of around 1%. Type I error and power were evaluated at an α of 0.05.

β₁	θ₂	Joint	Product	Bootstrap
0	0	0.0026	0.0001	0.0017
0	0.14	0.0065	0.0005	0.0043
0.14	0	0.0509	0.0463	0.0592
0	0.39	0.0351	0.0064	0.0286
0.39	0	0.0509	0.0505	0.0592
0.14	0.14	0.1310	0.1226	0.1398
0.14	0.39	0.6795	0.6652	0.6730
0.39	0.14	0.1322	0.1309	0.1397
0.39	0.39	0.6884	0.6869	0.6839