Table 1.
Baseline Characteristics of the 1273 HEMO Participants
| Characteristics | Results |
|---|---|
| Total P-Cresol Sulfate, mg/dL | |
| Mean ± SD | 3.3 ± 1.7 |
| Median [25th to 75th percentiles] | 3.3 [2.2–4.4] |
| Total Indoxyl Sulfate, mg/dL | |
| Mean ± SD | 2.5 ± 1.2 |
| Median [25th to 75th percentiles] | 2.4 [1.7–3.3] |
| Total Hippurate, mg/dL | |
| Mean ± SD | 5.4 ± 4.3 |
| Median [25th to 75th percentiles] | 4.5 [2.3–7.4] |
| Total Phenylacetylglutamine, mg/dL | |
| Mean ± SD | 4.5 ± 2.8 |
| Median [25th to 75th percentiles] | 4.0 [2.5–6.0] |
| Demographics | |
| Age, years | 57.5 ± 14.0 |
| Sex, Female % | 723 (56.8) |
| Race, Black % | 799 (62.8) |
| Clinical Characteristics | |
| Diabetes, % | 574 (45.1) |
| Cardiac Disease, % | 1003 (78.8) |
| ICED Score, % | 2.0 ± 0.8 |
| Gastrointestinal Disease, % | 477 (37.5) |
| Residual Kidney Urea Clearance, ml/min/35L TBW | 0.3 ± 0.5 |
| Body Mass Index, Kg/m2 † | 25.7 ± 5.4 |
| Body Surface Area, m2 † | 1.8 ± 0.2 |
| Dialysis Characteristics | |
| Years of prior dialysis | 3.5 ± 4.1 |
| Predialysis Systolic Blood Pressure, mm Hg † | 152.4 ± 25.8 |
| Post Dialysis Weight, Kg † | 70.0 ± 15.3 |
| Relative Volume Removed, % † | 4.1 ± 1.7 |
| Dose Intervention | 633 (49.7) |
| Flux Intervention | 632 (49.6) |
| Treatment Time, min † | 206.8 ± 28.3 |
| Blood Flow Rate, ml/min † | 343.0 ± 60.7 |
| Dialysate Flow Rate, ml/min † | 673.3 ± 129.8 |
| Predialysis Laboratory Tests | |
| Blood Urea Nitrogen, mg/dL † | 59.7 ± 18.8 |
| Single-pool Kt/VUREA † | 1.5 ± 0.3 |
| Serum albumin, g/dL † | 3.6 ± 0.4 |
| Serum β2-microglobulin, mg/L † | 36.7 ± 14.2 |
| Nutritional Parameters | |
| Equilibrated nPCR, g/kg/day † | 1.0 ± 0.3 |
| Adjusted protein intake, g/kg/day (ABW)* | 0.9 ± 0.3 |
| Fat, % | 35.5 ± 7.6 |
| Carbohydrate, % | 48.4 ± 9.3 |
Abbreviations: SE, Standard Error; ICED, Index of Coexistent Disease; Equilibrated nPCR, equilibrated normalized protein catabolic rate; TBW, total body water; SD, Standard Deviation; IQR, Interquartile Range [25th to 75th percentiles]; ABW, adjusted body weight
Data are presented as Mean ± SD or Median [IQR] for continuous variables and N (%) for categorical variables.
Measured at the same time as solutes. Remaining variables are measured at baseline.
If body weight was <90% or >120% of median standard body weight (SBW) as determined from the National Health and Nutrition Examination Survey II (NHANES II) data then protein intakes were normalized to an adjusted body weight (ABW) to standardize nutrient intake using the formula: ABW = ([Actual weight - SBW)] × 0.25) + SBW.26