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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Neurobiol Dis. 2017 Sep 18;109(Pt A):25–32. doi: 10.1016/j.nbd.2017.09.006

Figure 5.

Figure 5

Mecp2-null mice had larger THIP-induced currents in the NTS. A. Example traces of THIP-induced current responses before and during bicuculline perfusion from one WT and one Mecp2-null mouse. B. Group data of changes in current from baseline (before THIP application) showing enhanced THIP-induced currents in neurons recorded from the Mecp2-null mice (Fisher's LSD post-hoc test: *, p < 0.05 WT vs. Mecp2-null; §, p < 0.05 THIP vs. Bicuculline within the same genotype). C. Group data of noise variance before THIP application (Baseline), during THIP, and during THIP + bicuculline (bicuculline). THIP significantly increased noise variance in both groups. Each line on top indicates p < 0.05 between the two bars, Fisher's LSD post-hoc test.