Skip to main content
. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Kidney Int. 2017 Jul 27;92(6):1444–1457. doi: 10.1016/j.kint.2017.04.026

Figure 1. Role of RA and RARα in NTS-induced GN.

Figure 1

(a) Representative images of Periodic acid-Schiff (PAS)-stained kidney sections are shown for Pod-Rara+/+ and Pod-Rara−/− mice injected with vehicle (PBS), NTS only (NTS) or NTS with RA treatment (NTS+RA). Arrowheads show NTS-induced glomerular crescents (magnification: x200, scale bar: 50μm). (b) Quantification of percentage of glomeruli with crescents. (c) Development of proteinuria was assessed by urinary albumin to creatinine ratio (UACR). (d) Measurement of blood urea nitrogen levels. (*P<0.05 and ***P<0.001, compared to respective PBS-injected control; ##P<0.01 and ###P<0.001 compared to respective NTS-injected mice; §P<0.05 and §§P<0.01 compared to NTS+RA Pod-Rara+/+; n=6 in each group, n.d., not detected.)