Table 1. Subject characteristics by estimated GFR.
| eGFR 60+ | eGFR 45-60 | eGFR 30-45 | eGFR 15-30 | eGFR < 15 | |
|---|---|---|---|---|---|
| N | 92 | 91 | 106 | 102 | 34 |
| Age, years | 49.9 (±12.1) | 57.3 (±11.6) | 63.1 (±13.3) | 60.6 (±14.9) | 61.0 (±12.6) |
| BMI, kg/m2 | 30.8 (±8.3) | 31.9 (±6.8) | 31.2 (±8.3) | 31.3 (±7.9) | 30.2 (±6.2) |
| eGFR (ckdepi), mL/min/1.73m2 | 82.8 (±20.6) | 53.9 (±9.0) | 39.0 (±6.7) | 22.7 (±4.7) | 11.5 (±4.1) |
| Female gender | 25 (27.2) | 19 (20.9) | 30 (28.3) | 25 (24.5) | 6 (17.6) |
| Prevalent Diabetes | 38 (41.3) | 47 (51.6) | 58 (54.7) | 50 (49.0) | 21 (61.8) |
| Prevalent CAD | 19 (20.7) | 29 (31.9) | 41 (38.7) | 42 (41.2) | 7 (20.6) |
| Race | |||||
| White | 56 (60.9) | 59 (64.8) | 74 (69.8) | 60 (58.8) | 22 (64.7) |
| Black | 29 (31.5) | 24 (64.8) | 23 (21.7) | 31 (30.4) | 6 (17.6) |
| Other | 7 (7.6) | 8 (64.8) | 9 (8.5) | 11 (10.8) | 6 (17.6) |
| Statin use | 43 (46.7) | 53 (58.2) | 59 (56.2) | 63 (62.4) | 17 (51.5) |
| Current smoking | 22 (24.2) | 22 (24.7) | 16 (15.5) | 20 (20.2) | 7 (21.9) |
| HDL cholesterol,mg/dL | 42.1 (±20.6) | 38.7 (±14.9) | 42.0 (±15.9) | 39.2 (±14.5) | 35.3 (±12.1) |
| LDL cholesterol,mg/dL | 113.6(±55.1) | 92.6 (±33.7) | 101.4 (±41.8) | 100.3 (±41.7) | 90.9 (±35.9) |
| Triglycerides, mg/Dl | 157.9(±126.7) | 168.4(±110.5) | 152.1(±109.5) | 164.0(±133.1) | 167.1 (±115.0) |
| Total cholesterol, mg/Dl | 183.5 (±67.3) | 161.9 (±41.9) | 174.9 (±54.5) | 173.4 (±61.1) | 158.1 (±42.8) |
| Urine ACR (median, IQR) | 65.3 (9.2, 451.5) | 30.4 (3.7, 337.2) | 73.1 (11.7, 452.1) | 189.8 (43.5, 783.3) | 484.0 (179.1,1510.3) |
| CRP (median, IQR) | 1.9 (0.7, 4.4) | 3.0 (1.2, 6.4) | 2.8 (0.8, 7.7) | 3.0 (1.0, 7.3) | 2.0 (0.7, 6.4) |
Clinical and demographic characteristics of subjects classified by eGFR. Normally distributed data are presented as mean(±SD), and non-normally distributed data are presented as median(interquartile range). Diabetes and CAD prevalence, race, gender, smoking status, and statin use are presented as number of subjects (%). CAD is defined as any history of myocardial infarction, cardiac arrest, coronary artery bypass graft, or percutaneous coronary intervention. eGFR=estimated glomerular filtration rate, BMI=body mass index, CAD=coronary artery disease, HDL=high-density lipoprotein, ACR=albumin:creatinine ratio, CRP=C-reactive protein