Table 2.

HPV Risk Factors in Unvaccinated Study Participants with FA

Variable	Variable Levels	HPV Seronegative (N=23)		HPV Seropositive (N=16)		P
		N	%	N	%
Age (years)	0–8	9	39%	2	13%	0.06
	9–14	9	39%	4	25%
	15–18	2	9%	2	13%
	>18	3	13%	8	50%
Birth Method	Vaginal	14	61%	9	56%	1.00
	C-Section	9	39%	7	44%
Mother Abnormal Pap	No	14	88%	10	100%	0.51
	Yes	2	13%	0	0%
Fed Breast Milk as an Infant	No	9	39%	5	33%	1.00
	Yes	14	61%	10	67%
History of Sexual Experience	No	21	91%	8	50%	0.007
	Yes	2	9%	8	50%
History of Genital Warts	No	23	100%	15	94%	0.41
	Yes	0	0%	1	6%
History of Common Warts	No	15	94%	10	77%	0.30
	Yes	1	6%	3	23%
Reported Primary Smoking	No	23	100%	15	94%	0.41
	Yes	0	0%	1	6%
SHS Exposure	No	17	77%	8	50%	0.10
	Yes	5	23%	8	50%
Alcohol Consumption	No	23	100%	14	88%	0.16
	Yes	0	0%	2	13%
History of Blood Transfusion	No	10	43%	5	31%	0.52
	Yes	13	57%	11	69%
History of HSCT	No	14	61%	9	56%	1.00
	Yes	9	39%	7	44%

Note: HPV seropositivity was determined by the M4ELISA. HPV seropositive participants were those positive for one or more HPV types. Age at blood draw was evaluated as both a continuous and categorical variable. Frequencies (N) and percentiles (%) were provided for all variables and differences were evaluated using Fisher’s exact tests on non-missing values. Mother abnormal pap was specific to the 3 years prior to childbirth. Mother abnormal pap, secondhand smoke (SHS) exposure, and common warts had missing values which were not included in the percentages. C-section refers to cesarean section. HSCT, hematopoietic stem cell transplant. Bold p-values indicate that significant differences were observed (p-value ≤ 0.05).