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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: J Mol Med (Berl). 2017 May 20;95(9):905–913. doi: 10.1007/s00109-017-1544-2

Figure 2. Summary of the tryptophan (Trp) metabolism pathway including the enzymes involved in the primary metabolism of Trp.

Figure 2

From left to right: The enzyme indoleamine 2,3-dioxygenase-1 (IDO1) converts Trp to kynurenine (Kyn), host microbes producing tryptophanases catabolize Trp into indole metabolites, and Trp hydroxylase produces serotonin from Trp.