Table 1. The IC50 values (μM) of various chemotherapeutic agents on cell viability in breast cancer cell lines.
Cells | Doxorubicin | Pirarubicin | Epirubicin | Paclitaxel | CDDP |
---|---|---|---|---|---|
MCF-7/Con1600 | 1.81 ± 0.45 | 0.50 ± 0.08 | 10.00 ± 0.42 | 1.95 ± 0.56 | 7.98 ± 3.86 |
MCF-7/Dox1600 | 270.00 ± 46.00* | 19.19 ± 7.58* | 228.24 ± 127.66* | 294.23 ± 178.02* | 21.76 ± 4.89* |
MCF-7/Dox/NC | 302 ± 87.91* | 20.90 ± 2.31* | 175.55 ± 105.25* | 278.01 ± 46.43* | 18.66 ± 6.06* |
MCF-7/Dox/shH19 | 26.32 ± 1.81#*& | 3.44 ± 1.63#*& | 32.65 ± 7.54#*& | 9.38 ± 3.36#*& | 19.38 ± 4.65* |
*p < 0.05 compared to MCF-7/Con1600 group; #p < 0.05 compared to MCF-7/Dox/NC group; &p < 0.05 compared to MCF-7/Dox1600 group.