Figure 4. Micro-SPECT/CT images of 177Lu-PCTA-cetuximab in SNU-1066 HNSCC xenograft model.
(a) At 7 days post-injection of 177Lu-PCTA-cetuximab (12.95 MBq/100 μg), SPECT/CT volume and coronal section images were acquired for 2 h with small animal SPECT/CT system (Bioscan). (b) In blocking experiment, SPECT/CT volume and coronal section images were acquired by 2 h pre-injection of excess cetuximab before administration of 177Lu-PCTA-cetuximab. Tumors are indicated by white dotted circles.