Table 1. Clinical characteristics of 104 patients with PNH.
| Characteristic | Whole cohort | With thrombosis | Without thrombosis | P value |
|---|---|---|---|---|
| Cases, n (%) | 104 (100) | 17 (16.3) | 87 (83.7) | |
| Age (years) | 42.70±15.39 | 38.94±10.11 | 43.44±16.16 | 0.144 |
| Male gender, n (%) | 56 (54) | 9 (53) | 47 (45) | 0.935 |
| Bone marrow failure, n (%) | 43 (41) | 9 (53) | 34 (39) | 0.289 |
| PNH clone size (%) | 63.48±35.53 | 86.24±19.90 | 59.03±36.27 | <0.001 |
| Blood cells counting | ||||
| Reticulocytes (%) | 4.69±3.29 | 4.12±2.02 | 4.82±3.51 | 0.429 |
| Leukocytes (×109/L) | 4.01±1.91 | 4.31±2.28 | 3.95±1.84 | 0.49 |
| Hemoglobin (g/L) | 79.80±24.55 | 80.69±18.35 | 79.64±25.63 | 0.876 |
| Platelets (×109/L) | 109.51±85.55 | 93.94±98.41 | 112.44±83.24 | 0.43 |
| Hemolytic parameters | ||||
| Lactate dehydrogenase (U/L) | 1211.40±883.60 | 1115.31±713.73 | 1231.36±917.73 | 0.635 |
| Total bilirubin (μmol/L) | 27.54±21.73 | 27.68±19.41 | 27.52±22.27 | 0.979 |
| Conjugated bilibubin (μmol/L) | 7.43±4.23 | 8.32±3.86 | 7.25±4.30 | 0.36 |
| Unconjugated bilibubin (μmol/L) | 20.11±19.34 | 19.36±17.49 | 20.26±19.79 | 0.865 |
| Hematuria, n (%) | 44 (42) | 7 (41) | 37 (43) | 0.918 |
| Thrombotic parameters | ||||
| Protein C (%) | 111.04±21.01 | 110.63±27.01 | 111.12±19.87 | 0.932 |
| Protein S (%) | 105.96±19.91 | 101.56±25.70 | 106.80±18.69 | 0.338 |
| Fibrinogen (g/L) | 2.55±0.71 | 2.79±1.14 | 2.50±0.59 | 0.323 |
| D-dimer (mg/L) | 0.46±0.52 | 0.63±0.80 | 0.43±0.45 | 0.324 |
| Antithrombin (%) | 113.67±14.79 | 117.38±18.28 | 112.95±14.05 | 0.276 |
P value represented the significance of the data between patients with and without thrombosis.