Table 1. Characteristics of microarray and RNA-seq datasets included in the study.
| First author (publication year) | Country | Data source | Test method/Platform | Cancer group | Normal controls | Mean1±SD1 | Mean0±SD0 | AUC |
|---|---|---|---|---|---|---|---|---|
| TCGA (2017) | USA | TCGA | NR | 415 | 35 | 11.77±1.13 | 9.11±1.71 | 0.915 |
| Hippo Y et al. (2005) | Japan | GEO: GSE2685 | Affymetrix GPL80 | 22 | 8 | 7.32±0.43 | 7.40±0.46 | 0.426 |
| Wang G et al. (2013) | USA | GEO: GSE29272 | Affymetrix GPL96 | 134 | 134 | 6.74±0.53 | 6.54±0.44 | 0.594 |
| Holbrook JD et al. (2012) | Singapore | GEO: GSE29998 | Illumina GPL6947 | 50 | 49 | 6.18±0.66 | 5.76±0.72 | 0.648 |
| Cheng L et al. (2012) | China | GEO: GSE33335 | Affymetrix GPL5175 | 25 | 25 | 5.37±0.70 | 4.05±0.48 | 0.918 |
| Wu YH et al. (2012) | Singapore | GEO: GSE37023 | Affymetrix GPL96 | 112 | 39 | 5.83±0.55 | 6.24±0.59 | 0.286 |
| Kang M et al. (2014) | South Korea | GEO: GSE51575 | Agilent GPL13607 | 26 | 26 | 7.88±0.98 | 7.08±0.69 | 0.743 |
| Lin J et al. (2013) | USA | GEO: GSE52138 | Affymetrix GPL96 | 13 | 7 | 6.70±0.60 | 6.13±0.301 | 0.769 |
| Liu B et al. (2017) | China | GEO: GSE54129 | Affymetrix GPL570 | 111 | 21 | 6.21±0.69 | 4.63±0.28 | 0.988 |
| Wang J et al. (2014) | China | GEO: GSE56807 | Affymetrix GPL5175 | 5 | 5 | 7.11±0.92 | 5.11±1.01 | 0.960 |
| Zhang X et al. (2014) | China | GEO: GSE63089 | Affymetrix GPL5175 | 45 | 45 | 6.81±0.90 | 5.21±0.60 | 0.934 |
| Yoshizawa JM et al. (2015) | USA | GEO: GSE64951 | Affymetrix GPL570 | 63 | 31 | 7.93±1.71 | 8.00±1.88 | 0.485 |
| Hao L et al. (2015) | China | GEO: GSE65801 | Agilent GPL14550 | 32 | 32 | 6.18±1.69 | 7.01±2.02 | 0.378 |
| Shao Q et al. (2016) | China | GEO: GSE79973 | Affymetrix GPL570 | 10 | 10 | 6.11±1.12 | 5.11±0.89 | 0.800 |
| Wang B et al. (2016) | China | GEO: GSE84787 | Agilent GPL17077 | 10 | 10 | 6.40±3.54 | 5.91±2.99 | 0.570 |
| Cui J et al. (2013) | USA | Oncomine | Affymetrix GPL5175 | 80 | 80 | 5.73±1.54 | 4.45±1.55 | 0.732 |
| D'Errico M et al. (2010) | Italy | Oncomine | Affymetrix GPL570 | 38 | 31 | 9.18±0.71 | 8.26±0.69 | 0.818 |
| Wang Q et al. (2010) | China | Oncomine | Affymetrix GPL570 | 12 | 15 | 8.07±1.09 | 7.39±1.23 | 0.656 |
| Cho JY et al. (2011) | USA | Oncomine | Illumina GPL6884 | 71 | 19 | 7.24±0.71 | 7.46±0.80 | 0.353 |
| Sun YH et al (2014) | China | CNKI | RT-PCR | 60 | 60 | 0.38±0.07 | 0.05±0.03 | NR |
| Tang M et al. (2014) | China | CNKI | RT-PCR | 60 | 60 | 0.19±0.05 | 0.06±0.01 | NR |
AUC: area under curve
Note: Mean1±SD1: gastric cancer tissues; Mean0±SD0: non-tumor tissues.