Table 3. The relationships between PLK1 overexpression and clinicopathological significance in gastric cancer patients.
Clinicopathological features | Studies (n) | Patients (n) | Meta-analysis model | OR (95% CI) | P | Heterogeneity | |
---|---|---|---|---|---|---|---|
I2(%) | p | ||||||
Lymph node metastasis | 12 | 1395 | random effects model | 1.78(1.13–2.80) | 0.013 | 64.2 | 0.001 |
TNM stage | 15 | 1937 | random effects model | 1.48(1.02-2.15) | 0.038 | 63.6 | <0.001 |
Age | 8 | 1006 | random effects model | 1.19(0.77-1.84) | 0.437 | 53.2 | 0.037 |
Gender | 15 | 1915 | fixed effects model | 0.87(0.71-1.07) | 0.191 | 23.2 | 0.197 |
Tumor histology grade | 13 | 1447 | random effects model | 1.07(0.66-1.73) | 0.783 | 64.9 | 0.001 |
Depth of tumor invasion | 12 | 1405 | random effects model | 1.70(0.97-2.98) | 0.061 | 78.6 | <0.001 |
Metastasis | 5 | 667 | fixed effects model | 1.37(0.79-2.37) | 0.209 | 31.9 | 0.209 |
TNM: tumor node metastasis.