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. 2017 Sep 30;8(54):92497–92521. doi: 10.18632/oncotarget.21438

Table 3. The relationships between PLK1 overexpression and clinicopathological significance in gastric cancer patients.

Clinicopathological features Studies (n) Patients (n) Meta-analysis model OR (95% CI) P Heterogeneity
I2(%) p
Lymph node metastasis 12 1395 random effects model 1.78(1.13–2.80) 0.013 64.2 0.001
TNM stage 15 1937 random effects model 1.48(1.02-2.15) 0.038 63.6 <0.001
Age 8 1006 random effects model 1.19(0.77-1.84) 0.437 53.2 0.037
Gender 15 1915 fixed effects model 0.87(0.71-1.07) 0.191 23.2 0.197
Tumor histology grade 13 1447 random effects model 1.07(0.66-1.73) 0.783 64.9 0.001
Depth of tumor invasion 12 1405 random effects model 1.70(0.97-2.98) 0.061 78.6 <0.001
Metastasis 5 667 fixed effects model 1.37(0.79-2.37) 0.209 31.9 0.209

TNM: tumor node metastasis.