Table 1. Patients’ characteristics.
Characteristics | N (%) | |
---|---|---|
Age (years) (n = 83) | ||
Median | 65 | |
Range | 40–80 | |
Performance status | ||
0 | 75 (90) | |
1 | 6 (7) | |
2 | 2 (2) | |
Sex | ||
Male | 79 (95) | |
Female | 4 (5) | |
Follow up (month) | ||
Median | 32 | |
Range | 2–127 | |
Progression-free survival(month) | ||
Median | 24 | |
Range | 1–127 | |
Overall survival (month) | ||
Median | 32 | |
Range | 2–127 | |
Current status | ||
Dead | 48 (58) | |
Alive | 35 (42) | |
Smoking status | ||
Never | 5 (6) | |
Mild | 33 (40) | |
Heavy | 45 (54) | |
Alcohol status | ||
Never | 5 (6) | |
Moderate | 38 (46) | |
Heavy | 40 (48) | |
Differentiation | ||
Well differentiated | 30 (36) | |
Moderately differentiated | 42 (51) | |
Poorly differentiated | 11 (13) | |
Subsite | ||
Pyriform sinus | 70 (84) | |
Post cricoid | 6 (7) | |
Posterior wall | 7 (8) | |
T stage | ||
T1 | 0 | |
T2 | 15 (18) | |
T3 | 38 (46) | |
T4 | 30 (36) | |
N Stage | ||
N0 | 10 (12) | |
N1 | 13 (16) | |
N2 | 49 (59) | |
N3 | 11 (13) | |
Stage | ||
III | 16 (19) | |
IVA | 55 (66) | |
IVB | 12 (15) | |
NAC categories | ||
PF | 45 (54) | |
TPF | 38 (46) | |
Response to NAC | ||
Complete response | 0 | |
Partial response | 39 (47) | |
Stable disease | 34 (41) | |
Progressive disease | 10 (12) | |
Definitive treatment | ||
Surgery | 48 (58) | |
CCRT | 29 (35) | |
Palliation | 6 (7) | |
Postoperative treatment | ||
None | 20 (24) | |
RT | 20 (24) | |
CCRT | 8 (10) | |
HLA class I expression | ||
< 25% | 35 (42) | |
25–74 | 34 (41) | |
≥ 75% | 14 (17) | |
PD-L1 TPS | ||
< 1% | 57 (68) | |
1%–49% | 13 (16) | |
≥ 50% | 13 (16) |
NAC, neoadjuvant chemotherapy; PF, cisplatin and 5-fluorouracil; TPF, docetaxel, cisplatin, and 5-fluorouracil; TPS, tumor proportion score; CCRT, concurrent chemoradiotherapy.