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. 2017 Oct 6;8(54):92864–92879. doi: 10.18632/oncotarget.21638

Figure 4. WTD decreased spinal astrocytic expression of IL-1R1.

Figure 4

10 days after surgical operation, IL-1R1 has no co-localization with microglia marker of CD11b (a), and were primarily co-localized with astrocyte marker of GFAP (b). Immunofluorescence staining showed WTD (3.15-12.60 g/kg), but not pregabalin (25 mg/kg, p.o.), dose-dependently decreased IL-1R1/GFAP-IR cells in the superficial lamina of L5 spinal cord in SNL mice (c). Data are represented as mean ± SEM. ###P<0.001 vs. sham group, **P<0.01 and ***P<0.001 vs. SNL group.