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. 2017 Oct 6;8(54):92890–92903. doi: 10.18632/oncotarget.21641

Table 1. Clinicopathological patient characteristics.

Variable Value [mean ± SD (range)]
Age (yrs) 64 ± 15 (26 - 93)
Variable Value [median (95% CI)]
Follow-up time (ms) 46.7 (31.1 - 55.8)
Variable Value [n (%)]
Tumor stage pT1a 16 (16)
pT1b 67 (65)
pT2 15 (14)
pT3 1 (1)
ND 4 (4)
Depth of stromal invasion ≤ 1mm 12 (12)
> 1mm 75 (73)
ND 16 (15)
Lymph node involvement Present 31 (30)
Absent 40 (39)
ND 32 (31)
Metastasis Present 5 (5)
Absent 94 (91)
ND 4 (4)
Tumor grade 1 12 (12)
2 66 (64)
3 24 (23)
ND 1 (1)
Lymphovascular space invasion Present 8 (8)
Absent 80 (78)
ND 15 (14)
Haemangioinvasion Present 6 (6)
Absent 82 (80)
ND 15 (14)
Local surgical treatment Wide local excision 15 (15)
Partial vulvectomy 35 (34)
Vulvectomy 49 (47)*
Punch biopsy only 4 (4)**
Tumor-free margins Present 86 (84)
Absent 17 (16)
Lymph node dissection Sentinel 4 (4)
Inguinal (uni-, bilateral) 66 (64)***
No lymph node dissection 33 (32)
Radiation therapy Vulvar 12 (12)
Inguinal 8 (8)
Vulvar & inguinal 22 (21)****
No radiation 61 (59)
Chemotherapy Chemotherapy 1 (1)
Concurrent chemoradiation 3 (3)
No chemotherapy 99 (96)
Disease status No evidence of disease 64 (62)
Recurrent disease 36 (35)
Lost to follow-up 3 (3)
Outcome Alive 61 (59)
Tumor-related death 33 (32)
Non tumor-related death 8 (8)
Lost to follow-up 1 (1)

CI, confidence interval; ms, months; ND, not determined; SD, standard deviation; yrs, years.

*, includes 9 cases of concurent pelvic exenteration.

**, surgery was not performed due to death before surgery (2) or inoperable morbidity (2).

***, in 4 cases concurrent pelvic/paraaortic lymphadenectomy was performed.

****, in 12 cases concurrent pelvic/iliac radiation therapy was performed.