Table 2. Summary of staining and HPV analysis stratified by tissue compartment.
| Variable | Value [mean ± SD (range)] | |
|---|---|---|
| CD3+ T cells (n) | Epithelium | 23.31 ± 36.36 (0 - 143) |
| Stroma | 240.07 ± 357.42 (0.7 - 1478) | |
| CD20+ B cells (n) | Epithelium | 0.32 ± 2.46 (0 - 24) |
| Stroma | 46.58 ± 92.37 (0 - 503) | |
| CD68+ monocytes/macrophages (n) | Epithelium | 4.67 ± 8.32 (0 - 38) |
| Stroma | 22.97 ± 45 (0 - 378) | |
| Variable | Value [n (%)] | |
| PD-L1 immunoreactivity | Positive | 10 (10) |
| Negative | 93 (90) | |
| Ki-67 immunoreactivity | High | 29 (28) |
| Low | 56 (54) | |
| ND | 18 (18) | |
| p53 immunoreactivity | Positive | 21 (20) |
| Negative | 69 (67) | |
| ND | 13 (13) | |
| p16INK4a immunoreactivity | Positive | 30 (29) |
| Negative | 64 (62) | |
| ND | 9 (9) | |
| HPV high risk | Present | 31 (30) |
| Absent | 69 (67) | |
| ND | 3 (3) |
ND, not determined; SD, standard deviation.