Table 3. Grade 0~1 acute leukopenia VS. ≥ Grade 2 acute leukopenia dosimetry comparison.
| DVH parameters | acute leukopenia | t(z) | P | |||
|---|---|---|---|---|---|---|
| Grade 0-1 | range | ≥Grade 2 | range | |||
| PBM | ||||||
| V15% | 74.8 (27.63)* | 14.12-90.03 | 82(14.97)* | 55.2-92.5 | -2.073 | 0.038° |
| V20% | 66.52(31.12)* | 10.8-83.76 | 79(16.93)* | 50.7-91.5 | -2.471 | 0.013° |
| IBM | ||||||
| V20% | 54.41(29.38)* | 0-83.29 | 67.5(12.96)* | 43.1-80 | -2.6 | 0.009° |
| V25% | 39.9(20.98)# | 0-76.46 | 54.59(13.61)# | 26.1-78 | -2.769 | 0.01◊ |
| V35% | 16(16.32)* | 0-35.5 | 21.47(3.21)* | 6.9-46 | -2.12 | 0.043° |
| Dmean(cGy) | 2098(1076)* | 29-3193 | 2467(408)* | 1805-3358 | -2.166 | 0.03° |
| LPBM | ||||||
| V20% | 52.8(21.48)# | 2.35-90.41 | 69.6(26.62)# | 18-100 | -2.173 | 0.035◊ |
| V25% | 39.39(19.58)# | 0.99-72.58 | 55.42(26.13)# | 14.4-100 | -2.224 | 0.031◊ |
| V30% | 24.31(15.34)# | 0.18-52.37 | 37.46(23.1)# | 9.5-90 | -2.233 | 0.03◊ |
| LSBM | ||||||
| V15% | 87.17(36.44)* | 0-100 | 97.87(12.3)* | 86.4-100 | -2.097 | 0.036° |
| PTV (cm3) | 825.28(318.72)# | 94.27-1690.65 | 1067.52(400.67)# | 410.3-1796 | -2.103 | 0.041◊ |
◊independent samples T test, ○Mann-Whitney U test.
#Data presented as mean percentage, with standard deviation in parentheses.
*Data presented as median percentage, with quartile range in parentheses.
PBM= pelvic bone marrow; IBM= iliac bone marrow; LPBM= lower pelvis bone marrow; LSBM= lumbosacral Spine bone marrow; V15, V20, V25, V30, V35= volume of bone marrow receiving 15, 20, 25, 30, 35Gy or more; DVH= dose-volume histogram; Dmean= the mean dose of iliac bone marrow; PTV= planning Target Volume.