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. 2017 Oct 9;8(54):92943–92954. doi: 10.18632/oncotarget.21687

Table 2. Genetic polymorphisms and risk of lung cancer.

Genotype Lung cancer cases (%) Controls (%) P of HWE Adjusted OR a 95% CI P
Rs1049337 TT 133 (28.4) 118(25.9) 0.061 Ref
TC 234 (50.0) 207(45.5) 1.006 0.738,1.373 0.968
CC 101 (21.6) 130(28.6) 0.691 0.482,0.990 0.044*
Dominant model 0.882 0.659,1.179 0.395
Recessive model 0.688 0.510,0.929 0.015*
Additive model C allele 0.829 0.691,0.995 0.045*
Rs926198 TT 425(90.8) 385(84.6) 0.506 Ref
TC 42(9.0) 69(15.2) 0.552 0.367,0.830 0.004*
CC 1(0.2) 1(0.2) 0.910 0.056,14.674 0.947
Dominant model 0.557 0.372,0.834 0.005*
Recessive model 1.007 0.251,4.042 0.992
Additive mode C allele 0.583 0.396,0.860 0.006*

aAdjusted for age, ORs and 95% CIs were calculated by logistic regression. * P<0.05.