. 2017 Nov 16;8:932. doi: 10.3389/fphys.2017.00932

Table 3.

Enamel thickness and hardness of adult mandibular molars and incisors.

Genotype	N	Incisor enamel thickness (μm)	Molar enamel thickness (μm)	Molar enamel hardness (GPa)
Wild-type (C57BL/6J)	12	119.7 (4.3)^x	61.6 (3.8)^x	257.4 (64.6)
Amelogenin KO	12	19.1 (5.2)^w	11.5 (1.2)^w	217.2 (60.0)
M180Tg/CTRNCTg/LRAPTg/KO (++)	4	33.7 (10.9)^{w x}	33.4 (17.2)^{w x}	238 (87.4)
M180Tg/CTRNCTg/LRAPTg/KO (+)	4	28.1 (4.5)^w	33.4 (10.9)^{w x}	200.4 (61.6)
M180Tg/CTRNCTg/KO (++)	4	33.7 (11.4)^{w x}	23.7 (4.1)^{w x 3o}	150 (52.3)
M180Tg/CTRNCTg/KO (+)	4	41.6 (10.1)^{w x 3t}	36.0 (7.2)^{w x 2o}	294 (108.6)^x
M180Tg/LRAPTg/KO (+)^a	6	45.3 (4.5)^{w x 3o 3t 2o}	51.4 (7.6)^{w x 3o 3t 2o 2t}	265.0 (59.9)
CTRNCTg/LRAPTg/KO (+)^b	6	53.1 (14.7)^{w x 3o 3t 2o 2t}	41.4 (13.0)^{w x 3o 3t 2o}	190.2 (65.3)^{w 2t}
M180Tg/KO (+)^c^,^d	6	26.8 (9.6)^{w 2t}	43.0 (7.5)^{w x 3o 3t 2o}	291.2 (39.8)^{x 3t}
CTRNCTg/KO (+)^e	6	28.1 (11.7)^{w x 2t}	19.6 (3.9)^{w x 3o 3t 2t}	208.0 (75.0)^{w 2t}
LRAPTg/KO (+)^f^,^g	6	24.1 (7.3)^{w3o 2o 2t}	19.0 (2.2)^{w x 3o 3t 2t}	193.3 (66.5)^2t

Significant differences (p < 0.05) are indicated as follows: ^wfrom WT; ^xfrom Amelogenin KO; ^3ofrom M180Tg/CTRNCTg/LRAPTg/KO (++); ^3tfrom M180Tg/CTRNCTg/LRAPTg/KO (+); ^2ofrom M180Tg/CTRNCTg/KO (++); ^2tfrom M180Tg/CTRNCTg/KO (+).

Gibson et al. (2011);

Xia et al. (2016),

Li et al. (2008),

Pugach et al. (2013),

Pugach et al. (2010),

Chen et al. (2003),

Gibson et al. (2009).