Fig. 1.

On clinical examination, alopecia (a) and multiple fistula of a necrotizing right-sided cervical mass (b) are noted. CT scanning of the neck (c) reveals an inflammatory mass from the mucosal space extending to the skin from the nasal pharynx all the way down to the upper thoracic aperture, with multiple abscesses including one located prevertebral (arrow). The right carotid artery and jugular vein are taken up in the mass, with the vein being compressed. The left side shows multiple enlarged lymph nodes. The graph (d) shows the presence of IFN-γ autoantibodies in plasma of seven healthy controls (C, mean), one patient with a high concentration of strongly inhibiting IFN-γ autoantibodies (P1), the current patient (P2), and seven patients with NTM infections (NTM, mean) as measured by ELISA. Plates were coated with IFN-γ and plasma was allowed to bind before detection of the anti-IFN-γ autoantibodies with HRP-labelled anti-IgG