Figure 4. ELISA analysis for MMP-1, MMP-2, MMP-3, MMP-9, MMP-13, TIMP-1, and TIMP-2.

hPDLFs were incubated in the absence or presence of 10 ng/ml of IL-12 for 24 and 48 h, and then protein production in the supernatants of cultured PDLFs was assayed by ELISA. Data are represented as means ± S.E.M. of three independent experiments. *P<0.05 and **P<0.01, compared with the untreated group (0 ng/ml of IL-12).