Table 5.

Interaction analyses between LVEF (%) and beta-blockers vs. demographics and clinical and laboratory data in an explanatory analysis of HR ≤70 vs. >70 bpm in all patients with sinus rhythm and EF <40%

Interaction tested with variable	p value for interaction with LVEF	p value for interaction with BB
Age (years)	0.81	0.55
Sex	0.19	0.96
NT-pro-BNP (ng/L)	0.12	0.57
Hemoglobin (g/L)	0.30	0.89
Number of hospitalizations due to heart failure the past 2 years	0.90	0.83
Hypertension	0.20	1.00
BMI >30 kg/m2	0.76	0.95
Smoking	0.21	0.88
Diabetes	0.62	0.95
Heredity	0.15	0.95
Hypercholesterolemia	0.96	0.29
Ischemic heart disease	0.91	0.26
Primary valvular disease	0.69	0.97
Cardiomyopathy	0.38	0.23
Cardiac arrest	0.42
VES/VT	0.018
SVT	0.90
Bradycardia	0.50	0.92
Mild/moderate pulmonary disease	0.49	0.97
Severe pulmonary disease	1.00
Asthma	0.18
GFR (cat.)	0.062	0.89
Stroke without sequelae	0.29	0.97
Stroke with sequelae	0.35
Depression	0.12	0.97
Impotence	0.17	0.95
Malignancy (active)	0.96
Malignancy (stable)	0.46	0.97
Thyroid disease	0.26	0.98
Sitting systolic blood pressure (mmHg)	0.14	0.76
Sitting systolic blood pressure (cat.)	0.100	0.93
Standing systolic blood pressure (mmHg)	0.37	0.44
Standing systolic blood pressure (cat.)	0.63	0.49
LBBB	0.37	0.97
Chamber pacing	0.45	0.95
NYHA	0.44	0.27
Married/partner	0.62	0.93
Working	0.84	0.95
Retired	0.88	0.95