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. 2017 Oct 13;91(11):3561–3570. doi: 10.1007/s00204-017-2072-0

Fig. 1.

Fig. 1

Different options for the association behavior of CYP and mEH in the endoplasmic reticulum: a CYP and mEH remain essentially unassociated, or b CYP and mEH form a complex. The association of CYP and CPR is well established and thus can be used as a positive control. mEH microsomal epoxide hydrolase, CPR cytochrome P450 reductase, CYP cytochtome P450-dependant monooxygenase