. 2017 Nov 20;7:15873. doi: 10.1038/s41598-017-16221-8

Table 2.

Sense/antisense amino acid (aa) types for overlapping codons, F = −2 reading frame.

Amino acid classes produced by sense:antisense nucleotides
	nucleotide 2 or 2′
	U	C	A	G
nt 1 = U	L, F ∈ Φ	S ∈ π	Y ∈ Φ, stop	C, W, stop
nt 1′ = A	I, M ∈ Φ	T ∈ φ	N, K ∈ Π	S, R
nt 1 = C	L ∈ Φ	P ∈ φ	H, Q ∈ Π	R ∈ Π
nt 1′ = G	V ∈ φ	A ∈ φ	D, E ∈ Π	G ∈ π
Sense:antisense nucleotides needed to produce pairs of aa classes
sense class	antisense (1′2′3′) aa class
sense class	Φ	φ	Π	π
L, NP = Φ	U₁U₂:A_1′U_2′	U₁U₂:A_1′C_2′	U₁U₂:A_1′A_2′	A₁U₂:U_1′C_2′
S, NP = φ		C₁C₂:G_1′U_2′	G₁U₂:C_1′A_2′	G₁C₂:G_1′G_2′
L, P = Π			G₁A₂:C_1′A_2′	C₁A₂;G_1′G_2′
S, P = π			ambiguous → A₁G₂:U_1′C_2′

The relation between the sense/antisense overlapping codons and the nucleotide numbers are defined in Fig. 6.